Cloning used to make stem cells from adult humans in diabetes breakthrough
The disease kills insulin making cells in the pancreas.People with Type 1 diabetes use shots or a small pump to supply the hormone, which is needed to control blood sugar.The new work is a step toward providing genetically matched replacement cells for transplant, said Dieter Egli of the New York Stem Cell Foundation Research Institute in New York.He led [عزيزي الزائر يتوجب عليك التسجيل لمشاهدة الرابط للتسجيل اضغط هنا] the research, which was reported online Monday in the journal Nature.Doug Melton of the Harvard Stem Cell Institute, who was not involved with the work, called the paper an impressive technical achievement.The experiment in progress: A blastocyst derived after somatic cell nuclear transfer. The green fluorescence originates from the somatic cell genome and marks nuclei.Researchers [عزيزي الزائر يتوجب عليك التسجيل لمشاهدة الرابط للتسجيل اضغط هنا] are also exploring transplants of insulin producing cells from cadavers as a potential [عزيزي الزائر يتوجب عليك التسجيل لمشاهدة الرابط للتسجيل اضغط هنا] treatment.The latest work used a technique that partially resembles the process used to clone animals.Basically, scientists put DNA from the woman’s skin cells into donated human eggs.Egli told reporters that these cells have shown promise in animal tests, but that he could not estimate [عزيزي الزائر يتوجب عليك التسجيل لمشاهدة الرابط للتسجيل اضغط هنا] a ti****ble for human experiments.The new work is the third report of using the cloning approach to make human stem cells, and the first using the technique to create insulin making cells.Earlier [عزيزي الزائر يتوجب عليك التسجيل لمشاهدة الرابط للتسجيل اضغط هنا] this month scientists have moved a step closer to the goal of creating stem cells perfectly matched to a patient’s DNA in order to treat diseases, they announced yesterday.The advance, described online in the journal Cell Stem Cell, is the first time researchers have achieved ‘therapeutic cloning’ of adults.Technically called somatic cell nuclear transfer, therapeutic cloning means producing embryonic cells genetically identical to a donor, usually for the purpose of using those cells to treat disease.But nuclear transfer is also the first step in reproductive cloning, or producing a genetic duplicate of someone a technique that has sparked controversy since the 1997 announcement that it was used to create Dolly, the clone of a ewe.In 2024, the United Nations called on countries to ban it, and the United States prohibits the use of federal funds for either reproductive or therapeutic cloning.The study was funded by a foundation and the South Korean government.If confirmed by other labs, it could prove significant because many illnesses that might one day be treated with stem cells, such as heart failure and vision loss, primarily affect adults.
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